Supported by the Royal Academy of Engineering Research Fellowship, the BM² Lab was established in August 2025 under the leadership of Dr Tian Yuan.

                        

We develop multiscale and multiphysics modelling frameworks, underpinned by in vivo and in vitro experiments, to investigate transport and clearance processes in biological tissues. Our research focuses on optimising targeted drug delivery to the brain and solid tumours, elucidating mechanisms of glymphatic brain waste clearance and their role in neurological diseases such as Alzheimer’s disease, and advancing imaging-informed brain modelling for precision medicine.

       

By integrating mathematics, mechanics, biology and medical imaging, we develop predictive models that enable mechanistically grounded and personalised therapeutic strategies.

              

The lab builds on research directions developed with Prof. Daniele Dini at Imperial College London, while establishing an independent research programme.

                                                                                                             

Prospective PhD students and collaborators are welcome to get in touch!